HEMATOLOGICAL PROFILE AND IRON METABOLISM INDICATORS IN PREGNANT WOMEN LIVING IN MID-ALTITUDE AND LOW-ALTITUDE AREAS OF SOUTHERN KYRGYZSTAN
DOI:
https://doi.org/10.52754/16948610_2026_2_1%20Keywords:
pregnant women, anemia, hemoglobin, ferritin, serum ironAbstract
Relevance. This study aimed to assess the hematological profile of pregnant women with and without anemia living in a mid-altitude region (Aidarken) and a low-altitude area (Kara-Suu) in southern Kyrgyzstan. A total of 190 pregnant women in the third trimester, aged 19–45 years, were included in the study: Aidarken (n=106) and Kara-Suu (n=84). Hematological parameters including hemoglobin (HGB), red blood cells (RBC), hematocrit (HCT), mean corpuscular volume (MCV), serum ferritin, and serum iron were analyzed. The prevalence of anemia was 48.11% in Aidarken and 48.81% in Kara-Suu. In Aidarken, pregnant women with anemia had significantly lower hemoglobin levels (95.04 (10.22) vs. 122.73 (9.59) g/L; p<0.001), hematocrit (30.81 (5.48) vs. 38.19 (4.06)%; p<0.001), and MCHC (316.9 (21.24) vs. 332.2 (12.80) g/dL; p=0.009) compared with non-anemic women. In Kara-Suu, anemic pregnant women also demonstrated significantly lower hemoglobin levels (98.05 (9.85) vs. 120.35 (9.95) g/L; p<0.001), MCV (86.67 (8.66) vs. 90.82 (3.20) fL; p=0.0396), and serum ferritin concentrations (8.37 (2.04) vs. 12.58 (6.72) ng/mL; p=0.013) than non-anemic women. The findings indicate a high prevalence of anemia among pregnant women in both Aidarken and Kara-Suu. In the low-altitude area, anemia was associated with decreased serum ferritin levels.
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