THE VALUE OF SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B-LYMPHOCYTES DEPENDING ON THE DEGREE OF ACTIVITY OF UROGENIC REACTIVE ARTHRITIS

Authors

  • Askar Paizildaevich Irisov Osh State University
  • Gulnur Abdurahmanova Kulchinova Osh State University
  • Abdumitalip Tashalievich Mamasaidov Osh State University
  • Gulzada Ismailovna Zhamilova Osh State University

DOI:

https://doi.org/10.52754/16948610_2023_2_4

Keywords:

urogenic reactive arthritis, spontaneous immunoglobulin-synthesizing activity, B-lymphocytes

Abstract

This work considers the significance of spontaneous immunoglobulin-synthesizing activity of B-lymphocytes (SIAL) in various degrees of urogenic reactive arthritis (UReA). 53 patients with urogenic reactive arthritis aged 17 to 45 years (17 women and 36 men) were examined. I degree of activity of the pathological process was observed in 18 (33.9%) patients, II - in 22 (41.5%) and III degree - in 13 (24.5%) patients. It was found that an increased level of SIAL was found in patients with autoimmune diseases (AS, RA and SLE) from 72.2% to 88.8%, in 57.9% of UReA patients, only 10% of healthy individuals, and only 27.3% of osteoarthritis patients. It was shown that in UReA with a high degree of disease activity, the values of SIAL were higher than in I and II degrees of disease activity

References

Бадокин В. В. (2021) Реактивные артриты. Медпресс. Москва С. 97-102.

Балабанова Р. М. (2020) К вопросу о диагностике и кодировании реактивных артропатий. Современная ревматология.С. 41–44.

Белов Б.С. (2015) Реактивные артриты. С. В. Шубин, Р. М. Балабанова, Ш. Ф. Эрдес // Научно-практическая ревматология. С 414-420.

Варонько И. А. (2019) Современный взгляд на вопросы диагностики и лечения реактивных артритов. / И. А. Варонько // Рецепт. С. 877-885.

Мамасаидов А.Т. и.др. (2007) Спонтанная иммуноглобулинсинтезирующая активность В-лимфоцитов при воспалительных ревматических заболеваниях. Медицинская иммунология. С. 528-529.

Allen C. D. (2019) Cell Responses: Cell Interaction Dynamics and Decisions. / C. D. C. Allen // Cell. P. 524–540. DOI: https://doi.org/10.1016/j.cell.2019.03.016

Cheeti A. (2018) Reactive Arthritis. // StatPearls. Treasure Island (FL): Stat. Pearls. Publishing. P. 37-42.

Knox J. J. (2019) T-Bet+ Memory B Cells: Generation, Function, and Fate. // Immunol. Rev. 288: -Р. 149–160. DOI: https://doi.org/10.1111/imr.12736

Muilu P. et all. (2019) Increasing incidence and shifting profile of idiopathic inflammatory rheumatic diseases in adults during this millennium. / V. Rantalaiho, H. Kautiainen, L. J. Virta, J. G. Eriksson, K. Puolakka // Clin. Rheumatol. -P. 555-562. DOI: https://doi.org/10.1007/s10067-018-4310-0

Pavic K. et all. (2018) Acute arthritis: predictive factors and current practice in the approach to diagnosis and management across two hospitals in Sydney. / J. Pandya, S. Sebak, A. Shetty, D. Spencer, N. Manolios. // Intern. Med. J. -P. 1087-1095. DOI: https://doi.org/10.1111/imj.13969

Published

2023-06-29

How to Cite

Irisov , A. P., Kulchinova, G. A., Mamasaidov, A. T., & Zhamilova , G. I. (2023). THE VALUE OF SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B-LYMPHOCYTES DEPENDING ON THE DEGREE OF ACTIVITY OF UROGENIC REACTIVE ARTHRITIS. Bulletin of Osh State University, (2), 33–39. https://doi.org/10.52754/16948610_2023_2_4